Detection of pancreatic cancer with normal carbohydrate antigen 19-9 using protein chip technology
نویسندگان
چکیده
منابع مشابه
Relationship of carbohydrate antigen 19-9 and Lewis antigens in pancreatic cancer.
Carbohydrate antigen (CA) 19-9 identified by a murine monoclonal antibody against a colorectal carcinoma antigen is thought to be a sialylated Lewis (Le)a blood group antigen and occurs in high concentration in serum of patients with pancreatic carcinoma. This study was designed to identify the relationship between Lewis antigens and CA 19-9 in patients with pancreatic cancer. The following ana...
متن کاملPancreatic oncofetal antigen and carbohydrate antigen 19-9 in sera of patients with cancer of the pancreas.
Pancreatic oncofetal antigen (POA) and carbohydrate antigen 19-9 (CA 19-9) were measured in the sera of 23 patients with cancer of the pancreas to determine the true positive rates of these cancer markers. In one group of unselected pancreatic cancer patients (n = 9), both tests showed above-normal results in three patients and both gave values that were within reference limits in three other p...
متن کاملPancreatic Cancer with Normal CA 19-9 and Lewis Antigen Negative—Case Report
Pancreatic cancer is an aggressive and lethal disease that affects especially older population. Its more relevant tumor marker is CA 19-9 (carbohydrate antigen 19-9), although it can be elevated in others clinical situations, like cholangitis and cholestasis. Otherwise, a small people subset, like our patient, do not produce this tumor marker, as on blood as in the tumor, because they are incap...
متن کاملAdjusted carbohydrate antigen 19-9. Correlation with histological grade in pancreatic adenocarcinoma.
BACKGROUND The serum level of carbohydrate antigen 19-9 (CA 19-9) depends on the tumor size and differentiation grade. Jaundice can cause an elevation of serum CA 19-9, although the nature of this interaction is not fully understood. PATIENTS AND METHODS This was a retrospective study of 26 patients with potentially resectable pancreatic adenocarcinoma. Serum CA 19-9 was correlated with the h...
متن کاملPrognostic and therapeutic significance of carbohydrate antigen 19-9 as tumor marker in patients with pancreatic cancer.
In pancreatic cancer (PC) accurate determination of treatment response by imaging often remains difficult. Various efforts have been undertaken to investigate new factors which may serve as more appropriate surrogate parameters of treatment efficacy. This review focuses on the role of carbohydrate antigen 19-9 (CA 19-9) as a prognostic tumor marker in PC and summarizes its contribution to monit...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2014
ISSN: 1007-9327
DOI: 10.3748/wjg.v20.i40.14958